Enzymic release of carbon atom 8 from guanosine triphosphate, an early reaction in the conversion of purines to pteridines.
نویسندگان
چکیده
I E. R. B. GRAHAM ET A. GOTTSCHALK, Biochim. Biophys. Acta, 38 (z96o) 513. 2 S. HARBON, G. HERMAN, B. ROSSlGNOL, P. JOLL~S ET H. CLAUSBR, Biochem. Biophys. Res. Commun., 17 (1964) 57. 3 R. CARUBELLI, V. P. ]3HAVANANDAN ETA. GOTTSCHALK, Bioehim. Biophys. ,4eta, IOI (1965) 67. 4 L. A. ELSON ET W. T. J. MORGAN, Bioohem. J., 27 (1933) 1824. 5 J. L. REISSlG, J. L. STROMII~GER E~ L. FLELOIR, J. Biol. Chem., 217 (1955) 9596 F. MALEY ET G. V. MALEY, Biochim. Biophys..4eta, 31 (1959) 577. 7 S. ROSEMAN, Proc. 5th Intern. Congr. Biockem., New York, 1964, Abst r . vol. VI, p. 467 .
منابع مشابه
The Biosynthesis of Folic Acid. Iv. Enzymatic Synthesis of Dihydrofolic Acid from Guanine and Ribose Compounds.
In 1954, Albert (2) suggested that purmes may be biological precursors of pteridine compounds. This suggestion was made as a result of his demonstration that purines can be transformed chemically into pteridines under mild conditions in the presence of glyoxal. The first experimental evidence that the biogenesis of purines and pteridines are biologically related was provided by Weygand and Wald...
متن کاملInterferon- Gamma- Inducible Guanosine Triphosphate Cyclohydrolase 1 (GTP-CH1) Pathway Is Associated with Frailty in Egyptian Elderly
Background: Chronic low-grade inflammation may be a cardinal pathophysiologic feature in the pathogenesis of frailty. Interferon-gamma (INF-γ) is an understudied proinflammatory cytokine in frailty that induces many inflammatory pathways including the guanosine triphosphate cyclohydrolase 1 (GTP-CH1) pathway. Our aim was to evaluate the GTP-CH1 pathway in Egyptian frail elderly subjects. ...
متن کاملBiosynthesis of pteridines and of phenylalanine hydroxylase cofactor in cell-free extracts of Pseudomonas species (ATCC 11299a).
A cell-free system for the synthesis of a phenylalanine hydroxylase cofactor from guanosine triphosphate was obtained from extracts of Pseudomonas species (ATCC 11299a). This preparation produced formic acid from the ureido carbon of labeled GTP. The preparation also made specific pteridines from GTP. Among the products, xanthopterin, neopterin, and a cyclic phosphate derivative of neopterin we...
متن کاملCarbon catalyst derived from Himalayan pine for the C-N coupling of organic molecules leading to pyrrole formation
Carbon catalyst consisting of a hybrid structure made up of amorphous carbon and nanographite was prepared from the leaves of Pinus Roxburghii. The catalyst was prepared through sodium hydroxide and hydrochloric acid treatment of the dried pine leaves; and further functionalized with sulfuric acid treatment to incorporate the acidic functionalities. The synthesized catalyst was characterized by...
متن کاملCarbon catalyst derived from Himalayan pine for the C-N coupling of organic molecules leading to pyrrole formation
Carbon catalyst consisting of a hybrid structure made up of amorphous carbon and nanographite was prepared from the leaves of Pinus Roxburghii. The catalyst was prepared through sodium hydroxide and hydrochloric acid treatment of the dried pine leaves; and further functionalized with sulfuric acid treatment to incorporate the acidic functionalities. The synthesized catalyst was characterized by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Biochimica et biophysica acta
دوره 117 1 شماره
صفحات -
تاریخ انتشار 1966